Using this backpack is a breeze. Just unzip the compartments and place your items inside. The insulation pocket is great for keeping small bottles at the right temperature. For daily use, you can put your essentials like keys, wallet, and phone in the smaller compartments for easy access. When traveling, pack your clothes, toiletries, and other necessities in the larger sections. As for care, avoid exposing the backpack to sharp objects to prevent tears. If it gets dirty, you can gently wipe it with a damp cloth. Don't machine wash it as it may damage the waterproof coating. Also, make sure to empty the backpack regularly to prevent any unpleasant odors from building up. With proper use and care, this backpack will serve you well for a long time.